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Description

The similar chondrocyte defects noted in global and cartilage-specific IGF-1R knockout animals indicate that chondrocyte-derived IGF-1 is important for the maintenance of normal chondrocyte maturation

Methods and materials The RT-qPCR primers, siRNA sequences and construction primers for the KOD-Plus Mutagenesis Kit information used in this study are listed in Table S1, antibody information is listed in Table S2 and chemicals are listed in Table S3