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10.1016/j.jhep.2015.04.010 J Hepatol

Enhanced IL-1beta production in response to the activation of hippocampal glial cells impairs neurogenesis in aged mice

Hence, TP53 is classified as a tumor suppressor gene

Centrally, cagrilintide crosses the blood-brain barrier and activates receptors in key hypothalamic regions including the arcuate nucleus, area postrema, and lateral parabrachial nucleus