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For instance, administering 14,15-EET to CYP450 2J2 (CYP2J2)-overexpressing mice reduced NF-B expression, lipid peroxidation, and inflammation in the liver

For example, the pool of cytosolic glutathione is known to be highly reduced under standard growth conditions, but is susceptible to oxidation upon stress conditions, impacting different aspects of cell metabolism (Queval et al., 2011

However, the efficacy of KD could be influenced by cancer type, subtype, genetic features, or tumor-associated syndrome

Moreover, it is essential to investigate combination therapy, such as curcumin in conjunction with conventional treatments, and to conduct mechanistic research to elucidate pathways like Nrf-2 or PPAR-LXR-ABCA1