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mTORC2 exerts its various biological functions, including cell proliferation, survival and cytoskeletal organization, through phosphorylation of AGC kinases, including (protein kinase B) AKT, (protein kinase C) PKC and (serum- and glucocorticoid-inducible kinase 1) SGK-1 (Fig

Hospital Southampton NHS Foundation Trust, Southampton, UK Objective : Major trauma due to low-energy injury (MTLE) in the elderly population has become more common with higher mortality and increased frailty post-trauma

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