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Presynaptic cytoplasmic Ca 2+ can be depleted by several complementary mechanisms, including sarcoendoplasmic reticulum Ca 2+ -ATPase (SERCA) to the endoplasmic reticulum (ER), plasma membrane Ca 2+ -ATPase to the extracellular space, and MCU to the mitochondrial matrix [51,52,53]

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Emails that Panorama obtained from the time include an admission from Fudge that "whilst this process is completely within the WADA code there is a philosophical argument about whether this is within the 'spirit of the sport '" The idea of knowingly breaching the spirit but not the letter of the law was defiantly taken up by Farahs lawyer to Panorama