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Assays performed with leaf extracts of these lines indicated that GSAAT(C138S) and GSAAT(C396) are weakly stimulated by the addition of DTT (by up to 20% compared to their UT samples)

however, since activation of both CCR2 and CCR5 receptors directly activate hepatic stellate cells which promote hepatic fibrosis (433), further investigation on the effects of cenicreviroc on vSMCs are indicated to determine whether treatment affects atherosclerotic plaque stability

10.1016/j.cell.2013.12.010 109 YuY.JiangL.WangH.ShenZ.ChengQ.ZhangP.et al (2020)

10.1186/1477-3155-12-15 183 PerezL.ScarcelloE.IbouraadatenS.YakoubY.LeinardiR.AmbroiseJ.et al (2021)