Advocates argue that restricting the sale of fruit- and candy-flavored products would be another step toward preventing nicotine addiction in young people, while keeping open the option of vaping for recovering smokers who use e-cigs to help them avoid combustible cigarettes

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Interindividual variability in the metabolism and cardiovascular effects of nicotine in man, J Pharmacol Exp Ther 221 (2): 368-372
The lack of quality control presents challenges to toxicological investigation, with many published studies providing no information on the chemical content of e-liquids or their aerosols