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Mn overexposure also reduces glutamate receptor expression, NMDAR, in neurons in vitro and in vivo , potentially exacerbating glutamate-induced excitotoxicity (Wang et al., 2017

Additionally, they alleviate ROS-triggered transferrin receptor-induced iron uptake, lipid peroxidation and peroxidation-induced complex I inhibition, and aconitase in mitochondria [206]