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However, the mechanism may reasonably apply to GLP-1 therapy as well

Pericytes-mediated regulation of CBF Brain pericytes express contractile and cytoskeletal proteins that can modify CBF by adjusting their contractile tone and diameter [39, 99]

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From available case reports, compounding pharmacy data, and practitioner experience, the following have been observed: BPC-157 Reported Side Effects Nausea and gastrointestinal discomfort (especially with oral administration) Dizziness or light-headedness Flushing or warmth at injection sites Headache Fatigue or somnolence in some users TB-500 Reported Side Effects Injection site reactions (redness, mild pain, swelling) Transient fatigue or lethargy following administration Headache Possible flu-like symptoms in a minority of users Critical Risk Note: Because neither peptide has undergone full clinical trial evaluation in humans, the complete adverse event profile is unknown