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NF-b and HIF Crosstalk in Immune Responses

Increased levels of prostaglandin E2 (PGE 2 ) were demonstrated in homogenized small bowel biopsy specimens from patients with active celiac disease [34] while the levels of the antioxidant enzyme glutathione peroxidase and reductase were decreased in biopsies from celiac disease patients with consequent decreased levels of GSH [35,36,37] (Table 1)

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During periods of drug shortage, the FDA permits 503A compounding pharmacies to produce versions of the drug to meet patient demand