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Based on the pooled data across all evaluated PD-1/PD-L1 inhibitors, the eight most frequently reported respiratory adverse eventsdyspnoea, pneumonia, pneumonitis, interstitial lung disease, cough, pleural effusion, respiratory failure, and immune-mediated lung diseasewere selected to establish a common baseline for subsequent analyses

The peptide's selectivity is particularly notable when compared to other growth hormone secretagogues

Hospitalized patients with severe COVID-19 show high levels of IL-2, IL-7, IL-10, G-CSF, TNF, CXCL10, MCP1, and MIP1 in serum [6], suggesting that severe COVID-19 is dictated as a cytokine release syndrome (CRS), which is a disorder induced by cytokine storms [12,13,14]

A significant increase in its value was observed 24 hours after the intervention, and a significant decrease 48 hours after the intervention, as compared to its value after 24 hours (Paired T-test, 1 tailed, p=0.002, p=0.0005 respectively) ( Figure 1 )