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doi: 10.1095/biolreprod.112.102129 99 WangQZhanSLiuYHanFShiLHanCet al

Rather surprisingly, this suggests that the benefits of reduced mTORC1 signaling, and increased autophagy may be mediated primarily by an A-independent mechanism and moreover, previous studies have demonstrated that mTORC1 inhibition leads to the suppression of tauopathy 65,66