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& Monack, D

Dividing the total daily dose into smaller increments and consuming them with meals may help achieve this objective

Emerging evidence suggests a bidirectional relationship between gut health and brain function, often referred to as the gut-brain axis. Intestinal I/R injury, as a form of acute gut stress, has been implicated in triggering systemic inflammatory responses that extend beyond the gut, to impact distant organs, including the brain (Osadchiy et al., 2019)

FIGURE 10 4.1 The main takeaways Our conclusions can be viewed in the light of two different scenarios: (1) how can we achieve better target-site coverage with existing sprays, and (2) what are the insights here for the design of improved spray devices in the future