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Its coupling to GABA receptors-GABARs (/A, /B, /C) and their subunits induces the opening of K + ion channels to allow for the efflux of K + and the influx of Cl , resulting in hyperpolarization and a decrease in neuronal excitability (Sarasa et al., 2020)

This means that even if you dont have a true allergy, high levels of sulfite-induced histamine release could push you over the threshold and cause allergy-like symptoms