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Unlike GLP-1 agonists that work through appetite suppression, AOD-9604 directly enhances fat cell metabolism regardless of appetite or food intake

Genetic determinants of serum vitamin B12 and their relation to body mass index We found no support for a causal role of decreased serum vitamin B12 levels in obesity

All documented findings remain restricted to laboratory-based evaluation and analytical observation

First-line obesity treatments include lifestyle intervention (e.g., low-calorie diets) and behavioral modification therapies 4,5 since approved obesity medications have limited efficacy and commonly have side effects 6