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Conclusion: MASEF is a promising diagnostic tool for the assessment of at-risk NASH that can be used alternatively to LSM by VCTE in the FIB-4+LSM by VCTE algorithm that is currently recommended by the AGA and EASL

doi: 10.1007/s00005-012-0162-5 74 BlancoILaraBde SerresF

In reactive astrocytes, MAO-B activity is notably elevated, leading to increased production of H 2 O 2 , while NADPH oxidase 2 is frequently upregulated, further amplifying ROS generation [359, 363]