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Pregnancy and lactation represent relative contraindications given absence of human safety data in these populations despite reassuring preclinical reproductive toxicology studies

They found that standard aqueous solutions of AHK-Cu were ineffective because the hydrophilic peptide could not penetrate the sebum-rich environment of the hair follicle and was easily washed away during rinsing

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FIGURE 6 3.6 KYXC improves pathological status of mice aortic tissue Figures 6E, F display the results of HE and Masson staining of mice aortic tissue