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Much like Prx and TrxR1, Trx oligomerization is induced by oxidation, whereby Trx forms inactive dimers (Ren et al., 1993)

Srinivasan B (2021) A guide to the Michaelis-Menten equation: steady state and beyond

GHK-Cu also influences the ubiquitin-proteasome system (UPS), upregulating dozens of genes involved in protein degradation and cellular maintenance, thereby supporting proteostasis under stress conditions (Pickart and Margolina 2018)