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The approach will depend on the cause and severity of the deficiency

Duration of Study: Short-term acute studies (e.g., 24-48 hours) will naturally have a different 5-Amino-1MQ dosage profile than long-term chronic studies (e.g., 4-12 weeks)

This complex process means that conditions affecting the stomach or intestines can significantly impair B12 absorption, including pernicious anaemia, atrophic gastritis, previous gastric surgery, coeliac disease, Crohn's disease, and long-term use of certain medications (such as metformin, proton pump inhibitors, and H2 antagonists)