27 patients (2.7 %) were HDV RNA positive, 80% were male, mean age 44yo (SD15), 74% had advance fibrosis or cirrhosis and 3 patients (11%) were co infected by HIV
The duration of mushroom development varies among species
Collectively, these findings highlight the critical role of redox imbalance in AD development
Disclosures: Lorenza Rimassa: Jazz Pharmaceuticals, MSD, Nerviano Medical Sciences: Consultant, Roche, Servier, Taiho Oncology, Zymeworks: Consultant, AstraZeneca: Travel expenses, Agios, AstraZeneca, BeiGene, Eisai, Exelixis: Grant/Research Support, Fibrogen, Incyte, Ipsen, Lilly, MSD, Nerviano Med Sciences: Grant/Research Support, AbbVie, AstraZeneca, Basilea, Bayer, Elevar Therapeutics: Consultant, Exelixis, Genenta, Hengrui, Incyte, Ipsen, IQVIA: Consultant, AstraZeneca, Bayer, BMS, Guerbet: Speaking and Teaching, Incyte, Ipsen, Roche, Servier: Speaking and Teaching, Agios, AstraZeneca, BeiGene, Eisai, Exelixis, Fibrogen: Grant/Research Support, Incyte, Ipsen, Lilly, MSD, Nerviano Medical Sciences: Grant/Research Support, Roche, Servier, TransThera Sciences, Zymeworks: Grant/Research Support, Stephen Chan: MSD: Honoraria recipient, research grants, Ipsen: Honoraria recipient, research grants, Astra-Zeneca: Speaking and Teaching, Eisai: Speaking and Teaching, Roche: Speaking and Teaching, Bruno Sangro: Nothing to Disclose, George Lau: Nothing to Disclose, Masatoshi Kudo: Nothing to Disclose, Valeriy Breder: Roche: Speaking and Teaching, AstraZeneca: Speaking and Teaching, EISAI: Speaking and Teaching, Bayer: Speaking and Teaching, Swixx BioPharma: Speaking and Teaching, Maria Varela: Boston: Speaking and Teaching, Astra Zeneca: Consultant, Roche: Consultant, Oxana Crysler: Nothing to Disclose, Mohamed Bouattour: Bayer: Consultant, AstraZeneca: Consultant, MSD: Consultant, BMS: Consultant, SIRTEX Medical: Consultant, ROCHE: Consultant, Bayer: Advisor, Tu Van Dao: Nothing to Disclose, Adilson Faccio: Nothing to Disclose, Junji Furuse: Astra Zeneca: Speaking and Teaching, Ono Pharma: Speaking and Teaching, Chugai Pharma: Speaking and Teaching, Eisai: Speaking and Teaching, Servier: Speaking and Teaching, MSD: Advisor, Novartis Pharma: Speaking and Teaching, Takeda: Speaking and Teaching, Taiho Pharma: Speaking and Teaching, Daiichi Sankyo: Speaking and Teaching, Incyte Biosciences: Speaking and Teaching, J-Pharma: Advisor, Astellas: Advisor, Onco Therapy Science: Advisor, Delta-Fly-Pharma: Advisor, TME Therap: Advisor, Long-Bin Jeng: Nothing to Disclose, Yoon Koo Kang: Nothing to Disclose, Robin Kate Kelley: Astra Zeneca: Grant/Research Support, Bayer: Grant/Research Support, Eli Lilly: Grant/Research Support, Exelixis: Grant/Research Support, Genentech/Roche: Grant/Research Support, Kinnate: Consultant, Merck: Grant/Research Support, Partner Therapeutics: Grant/Research Support, Regeneron: Consultant, Agios: Grant/Research Support, BMS: Grant/Research Support, QED: Grant/Research Support, Tyra: Grant/Research Support, Taiho: Grant/Research Support, Surface: Grant/Research Support, Servier: Grant/Research Support, GSK: Consultant, moderna: Consultant, J Pharma Inc.: Consultant, Relay Therapeutics: Grant/Research Support, Michael Paskow: Nothing to Disclose, Mallory Makowsky: Nothing to Disclose, Di Ran: Nothing to Disclose, Alejandra Negro: Nothing to Disclose, Ghassan Abou-Alfa: Agenus, Arcus, Astra Zeneca, BioNtech, BMS, Elicio, Genentec: Grant/Research Support, Abbvie, Alligator Astra Zeneca, Autem, Berry Genomics, BioNt: Consultant 1850 IMMUNE-RELATED LIVER INJURY IS A GOOD PROGNOSTIC FACTOR IN PATIENTS WITH HEPATOCELLULAR CARCINOMA UNDER ATEZOLIZUMAB PLUS BEVACIZUMAB THERAPY Tai-Chi Wu 1 Wei Teng 1 Po-Ting Lin 1 Eric Yi-Liang Shen 1 Chung-Wei Su 1 Yi-Chung Hsieh 1 Wei-Ting Chen 1 Tsung-Han Wu 1 Chen-Chun Lin 1 Chun-Yen Lin 1 Shi-Ming Lin 1 , 1 Linkou Chang Gung Memorial Hospital Background: Atezolizumab plus bevacizumab therapy is the standard first-line therapy for unresectable hepatocellular carcinoma (HCC), and immune-related liver injury (IrLI) is commonly observed in these treated patients, especially with underlying chronic liver disease
