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It is a flavoenzyme that plays an important role in protection of cells against endogenous and exogenous quinones by catalyzing two- or four-electron reductions of these substrates [2]

Reductions in GABA levels found in patients with ALS in motor cortex compared to healthy controls (Foerster et al., 2012, 2013) may contribute to cortical hyperexcitability

Following FOXO4-DRI peptide evaluation, the researchers noted an apparent increase in markers such as 3-HSD and CYP11A1