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For instance, calcipotriol-loaded NLCs, especially when co-loaded with methotrexate (CAL-MTX-NLCs), demonstrated a significant improvement in skin targeting, with enhanced delivery of methotrexate (2.44.4 times) and reduced calcipotriol release, mitigating the risk of irritation (Lin et al

At the 24-month mark, the treated group exhibited a 75% increase in adjusted average C-peptide Area under the curve (AUC) compared to controls, although HbA1c levels showed no significant difference between the groups

Shao W, Espenshade PJ (2014) Sterol regulatory element-binding protein (SREBP) cleavage regulates golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP)

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