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The glucose-dependent nature of semaglutides insulin secretion generally results in a lower intrinsic risk of hypoglycemia compared to insulin or sulfonylureas, but the combination effect must be carefully managed

Diarrhea and constipation are also commonly observed, each potentially affecting ten to fifteen percent of patients, with individual susceptibility varying based on factors such as baseline gastrointestinal function, dietary habits, and concurrent medications

Must be reconstituted with bacteriostatic water prior to use

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