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However, abnormal mitophagy leads to the accumulation of dysfunctional mitochondria, exacerbating OS and A generation, thereby worsening AD pathology (Roca-Agujetas et al., 2021

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J Adv Res 6(34):4363 Echouffo-Tcheugui JB, Daya N, Ndumele CE, Matsushita K, Hoogeveen RC, Ballantyne CM, Coresh J, Shah AM, Selvin E (2022) Diabetes, GDF-15 and incident heart failure: the atherosclerosis risk in communities study