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Conclusion: We identify novel genetic risk variants and complex genetic architecture of cirrhosis and HCC in which metabolic dysfunction is both an independent risk factor and a multiplicative accelerator of disease risk when combined with a high genetic burden or other causes of liver disease

The appetite suppression that makes Retatrutide so effective also creates nutritional challenges that require deliberate management

doi: 10.1111/ajad.12809 [PubMed] 30500943 Quaye AN, Zhang Y

Special populations, such as post-bariatric surgery patients and those on metformin, may require tailored dosing regimens to ensure adequate vitamin B12 levels