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Interestingly, infants with congenital GH deficiency and GHR mutations present with only minor growth retardation, whereas the rare patient with IGF-I deficiency, secondary to a homozygous partial deletion of the IGF-I gene, presents with severe pre and postnatal growth failure, mental retardation, sensorineural deafness, and microcephaly (76-78)

The capsule shell can provide a relatively stable environment, extend the shelf life of drugs, and ensure that drugs can exert stable therapeutic effects within their effective period

Vegetarians and vegans can suffer from B12 deficiency, so can meat eaters, making B12 deficiency a common concern many people solve with supplementation or a B12 injection

Prescribing BPC-157 outside of clinical trials could lead to legal issues for physicians