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TBHQ serves as an Nrf2 activator, and studies have demonstrated that intervention with a combination of vanillin acetate and TBHQ in a TBI mouse model can activate Nrf2-related pathways, alleviate oxidative stress and protect the gray matter of the mouse brain [158,159]

Patients with melanoma have demonstrated good tolerance and activation of the cytotoxic T cell-facilitated immune response in phase I/II clinical trials (Speiser et al., 2010)

Immunomodulatory effects of pharmaceutical opioids and antipyretic analgesics: mechanisms and relevance to infection

A novel human CRYGD mutation in a juvenile autosomal dominant cataract