human glutathione synthetase enzymes synthesis: A two-step pathway. Homeostasis of cellular Cysteine metabolic circuitries: druggable targets

Structural basis for RNA replication by the SARS-CoV-2 polymerase Cell2020Wang, Q

Carion et al., TB-500 and Ciprofloxacin Adjunctive Therapy Improves Pseudomonas aeruginosa-Induced Keratitis, Cells, 7(10), 2018

The decrease of activity of SOD also led to a decrease in the efficiency of eliminating ROS, forming a vicious circle

It is therefore assumed that transcription from gdhA P2 serves to enhance gdhA expression when the concentration of -ketoglutarate is low, as during invasive disease, both to enhance the activity of the TCA cycle in the catabolic reaction, and to provide L-glutamate for glutathione biosynthesis in the anabolic reaction