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[92] suggested that the activation of brain areas that control emotional motivation, balance of emotions, and autonomic responses to pain in IBS-C patients differed from that in patients with the other IBS subtypes

Their broad protective actions highlight strong nutraceutical potential for disease prevention and treatment (74)

This phenomenon enhances the generation of ROS, which contribute to bacterial cell membrane disruption and oxidative stress-induced cell death (Canaparo et al., 2020)

However, during prolonged storage, folate contents gradually dropped, reaching 25% and 38% losses in the bread leavened with bakers yeast and in the bread fermented with sourdough, resp., after 16 weeks, likely due to air oxidation