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doi: 10.1016/j.bbadis.2015.01.015 105 SemchyshynHM

) 2953 (Springer, 2016)

Finally, the participants completed a sleep study to determine the effects of circadian rhythm on brown adipose tissue metabolism

Out of 22 patients, 10 patients experienced significant improvement by 50%, which highlighted the role of mitochondrial hypo-metabolism in the pathogenesis of primary ME/CFS [54]