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doi: 10.1016/j.biomaterials.2025.123239 150 DengYLuJLiWWuAZhangXTongWet al

In addition, NAMPT regulation of cancer stem cell pathways correlated with SIRT1 and PARP1, as these proteins seem to play important roles in the CSC phenotype acquisition promoted by NAMPT

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Moreover, the upregulation of GPX3 expression may confer protection to tumor stem cells against exogenous oxidative stress injury, thereby facilitating the maintenance of stemness characteristics in OCSCs