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Description

A Phase 1b Study of ALRN-6924 in Combination with Paclitaxel in Wild-type (WT) TP53 Metastatic Solid Tumors including Estrogen-Receptor Positive Breast Cancer

Additionally, PHOSPHO1 reduces autophagy and ferritin uptake, consequently decreasing the intracellular accumulation of free iron

These differential metabolites were mainly divided into two categories: one was 58 significantly downregulated differential metabolites compared to the CON group, mainly including oxypurinol, 2 - Deoxyuridine, Shikimate, Gamma aminobutyric acid, Indoleacrylic acid, and Dimethylbenzimidazole