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Some of these diagnostic tests include: A physical examination to check for symptoms such as heart murmur, pale skin, and brittle nails Blood tests, including tests to measure complete blood count (CBC), iron and vitamin levels, and reticulocytes (red blood cells that are not yet fully developed) Other tests to determine the cause, including bone marrow testing, endoscopy, colonoscopy, and urine testing Once the anemia is diagnosed and the cause is confirmed, the patients medical team will have better insight into how best to treat the condition