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This NAD+ elevation activates sirtuins, particularly SIRT1 in adipocytes and hepatocytes, which deacetylates and activates numerous metabolic regulatory proteins including PGC-1, a master regulator of mitochondrial biogenesis, oxidative metabolism, and thermogenesis

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In the case of atherosclerosis, it is generally accepted that the abnormal proliferation of VSMCs plays an important role in the pathophysiology of the disease 2, 3, 4

A purity of 99% indicates that 99% or more of the UV-absorbing material in the sample consists of the target peptide