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Suppression of selective voltage-gated calcium channels alleviates neuronal degeneration and dysfunction through glutathione S-transferase-mediated oxidative stress resistance in a Caenorhabditis elegans model of Alzheimers disease

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Given that lipophagy supplies FAs to boost FAO and TCA in mitochondria, we then reasoned that loss of LEC-autophagy could result in a concomitant downregulation of CPT1A levels, further impairing the overall capacity of the LEC to utilize FAs as energy source

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Michael acceptors Electrophiles that can react with a nucleophile through Michael addition, often containing an , -unsaturated carbonyl and an electron-withdrawing group

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PLoS One 9 , e103554 (2014)

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