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"Rhodiola rosea in stress induced fatiguea double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty." Phytomedicine 7.5 (2000): 365-371

Because of that, the amount actually used by the body may be limited

EP patent 146,265 Gushima H, Miya T, Murata K, Kimura A (1983) Construction of glutathione-producing strains of Escherichia coli B by recombinant DNA techniques