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The ingredients could act through two possible ways: (a) biological mechanism-oriented by exerting anti-photodamage actions, namely the products resulting of the direct and oxidative damage of DNA, downregulation the expression of MMPs, and pro-inflammatory cytokines confirmed in in vitro studies in keratinocytes and fibroblasts and in vivo and ex vivo studies, and/or (b) clinical effects-oriented by softening the visible effects of the skin sun damage, by providing moisturizing effect and refreshing properties, mainly corroborated by clinical trials

J., Mishra, B., DiChristina, T

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IL-10, IL-13, and IL-15) may have anabolic effects and modify the contractile function of the skeletal muscle