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Whereas genetic or pharmacologic inhibition of the necroptosis axis prevented activation of necroinflammation and subsequent development of renal fibrogenesis (Jiang et al., 2022

Figure 1: Showed the right mandibular edentulous ridge of a patient diagnosed with CTN and the fabricated stent to cover the painful site Pharmacological methods Pharmacological treatments include antidepressants (e.g., SSRIs, SNRIs, TCAs) and anticonvulsants (e.g., gabapentin, carbamazepine), which suppress neuronal hyperexcitability