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Flukes exhibit a wide range of modulatory mechanisms, including amplifying Th2-type cytokine release, reducing MHC II expression to disrupt antigen presentation, inducing Treg differentiation, among others, as reviewed elsewhere (345)

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FABP levels may vary according to disease severity as FABP1 protein levels were overexpressed in obese patients with steatosis ( n = 10) compared to obese controls ( n = 10), but decreased in NASH patients with mild fibrosis ( n = 10) and declining further in NASH with advanced fibrosis ( n = 10) [36]