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These functions make NAC supplementation a viable therapeutic option for various health issues

20 Primarily, NADPH provides reducing equivalents for fatty acid synthase (FASN), the main rate-limiting enzyme, to synthesize fatty acids with acetyl-CoA serving as a primer and malonyl-CoA as a two-carbon donor, 21,22 and provides the needed electrons for ironsulfur (Fe/S) protein assembly that participate in non-essential amino acid biosynthesis and lipoic acid synthesis, tRNA modification, DNA replication and repair, and telomere maintenance

Produced in the liver, glutathione assists with detoxifying xenobiotics and heavy metals, neutralizes hydrogen peroxide, maintains the integrity of blood cells, and helps transport amino acids across cell membranes

341,342 For elderly low-risk patients, the primary concern is how to predict the survival benefits of radiotherapy using limited information while avoiding its potential side effects