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Interestingly, the levels of these polyamines are significantly reduced in fibrotic lungs, and their supplementation has been shown to alleviate oxidative stress and attenuate fibrosis [16, 77,78,79]

J Gerontol 11:298300 Harman D (2009) Origin and evolution of the free radical theory of aging: a brief personal history, 19542009

There is growing evidence that ASD is associated with abnormalities in several metabolic pathways, including the inter-connected folate, methylation and glutathione pathways