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There has been a consistent level of concern within the industry about the tendency of the Commonwealth to introduce new price-reduction policies (including new interpretations of the reference pricing policy) and new legislation without sufficient warning, thereby eroding the ability of the industry to predict and manage the future prices of their products

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Prodrug strategies can improve drug metabolic stability and protect active drugs from metabolism by modifying the corresponding functional groups to mask easily metabolizable sites

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NICE guidance emphasises that treatment should not be delayed whilst awaiting confirmatory blood results if clinical suspicion is high

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Using RNA-seq transcriptomics, the regulatory impact of thiol-oxidation of NaOCl-sensitive transcription factors on the changes in gene expression was analyzed

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