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While Phase II trials in heart failure and primary mitochondrial myopathy did not meet primary efficacy endpoints, the TAZPOWER trial in Barth syndrome demonstrated significant improvements in muscle strength and sixminute walk distance, leading to FDA accelerated approval in 2025 [3] [10]

Conclusion About 60% of people don't get enough magnesium, making it a common but often missed health issue

doi: 10.1016/S0891-5849(02)00905-X 62 RheeSGWooHAKilISBaeSH

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