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A major limitation of the present study is the cross-sectional design of the analyses, which estimated the associations between AC levels and depression at the same assessment (either baseline or 6-year follow-up), precluding conclusions about causality

Potentially reduced mixing time: Some users find that creatine powder dissolves more easily in water when taken on an empty stomach, as stomach acid helps break it down more efficiently

Additionally, antibiotics like metronidazole and ciprofloxacin are frequently used for neurological disorders (Tang et al., 2013), but continuous antibiotic use to reduce TMAO can disrupt intestinal ecology, affecting beneficial gut flora, and TMAO levels can reappear a month or more after stopping antibiotics

This can expedite the recovery process, allowing you to get back to your workout routine sooner