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Nano Lett.6501504 61

Sinha, R., Fuse, T., Aubin, L

Within the BRH system, HYP serves as the primary therapeutic agent by inhibiting MAO activity and modulating neurotransmitter metabolism

There may be a higher risk of CRS early on for patients undergoing CAR T-cell therapy within the first 1 to 2 weeks, he noted, whereas with T-cellengaging therapy there is a relatively low risk of CRS once patients have made it through their ramp-up treatment state