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(2021) Modulating skin colour: role of the thioredoxin and glutathione systems, Antioxidants, [online]

Overall, these results suggest that Mn overexposure triggers multiple programmed cell death pathways, including apoptosis and ferroptosis, through mitochondrial dysfunction, ER stress, and impaired redox balance

Tay Sachs disease (GM2 Ganglioside) using targeted enzyme replacement therapy with alpha-hexosaminidase A or substrate inhibition of glucosylceramide synthase using imino sugars (e.g., miglustat (Zavesca marketed by Actelion) = N-butyl-deoxynojirimycin (NB-DNJ))