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A structural comparison of the wild-type AR bound to DHT and the agonist-converted AR-bicalutamide complex demonstrated that the sites that bind the A and B rings of DHT are similar to the sites bound by bicalutamide

The single cells and the cell spheroids used in the experiments are first prepared by culturing cells in conventional monolayer and 3D spheroid formats as shown in Figure 1A

Microscopically, the group treated with boswellic acid indicated an intact cellular framework along with no apparent signs of inflammation, showing the potent anti-inflammatory activity of boswellic acid

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