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These vary in the strength and consistency of supporting evidence, so it is useful to distinguish between the better-established findings and those representing a more preliminary evidence base

Systematic capture of dosing patterns, formulation source, route of administration, and standardized clinical outcomes may be more informative than continued reliance on heterogeneous mechanistic studies

The source of the specialty specific indirect percentage is the Physician Practice Information Survey (PPIS), last administered in 2007 and 2008, prior to the adoption of digital therapy technologies (86 FR 65037)

Methods and Results: Fifty-one patients completed all measurements