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Polymorphonuclear Myeloid-Derived Suppressor Cells Are Abundant in Per ipheral Blood of Cancer Patients and Suppress Natural Killer Cell Anti -Tumor Activity

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A groundbreaking approach introduced by Guo, Boda et al., outlines a novel cancer therapy tactic that involves the creation of a ROS-sensitive polymer, PHPM, which is utilized to concurrently encapsulate elesclomol and copper into nanoparticles, dubbed NP@ESCu

doi: 10.1038/nature05933 108 GerlingerMRowanAJHorswellSMathMLarkinJEndesfelderDet al