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Crit Care Med

Neurotypical control participants were eligible if they had no history of neurological or developmental disorders, no first-degree relatives diagnosed with ASD and were in good overall physical and mental health at the time of recruitment, as reported by parents or legal guardians

Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits

Endothelial dysfunction is characterized by abnormal vasoconstriction, leukocyte adherence to vascular endothelial cells, platelet activation and aggregation, smooth muscle cell proliferation, vascular inflammation, thrombosis (clot formation), impaired coagulation, and atherosclerosis (97)